Detection of 13 Ginsenosides (Rb1, Rb2, Rc, Rd, Re, Rf, Rg1, Rg3, Rh2, F1, Compound K, 20(<i>S</i>)-Protopanaxadiol, and 20(<i>S</i>)-Protopanaxatriol) in Human Plasma and Application of the Analytical Method to Human Pharmacokinetic Studies Following Two Week-Repeated Administration of Red Ginseng Extract

Detection of 13 Ginsenosides (Rb1, Rb2, Rc, Rd, Re, Rf, Rg1, Rg3, Rh2, F1, Compound K, 20(<i>S</i>)-Protopanaxadiol, and 20(<i>S</i>)-Protopanaxatriol) in Human Plasma and Application of the Analytical Method to Human Pharmacokinetic Studies Following Two Week-Repeated Administration of Red Ginseng Extract

We aimed to develop a sensitive method for detecting 13 ginsenosides using liquid chromatography&#8722;tandem mass spectrometry and to apply this method to pharmacokinetic studies in human following repeated oral administration of red ginseng extract. The chromatograms of Rb1, Rb2, Rc, Rd, Re, R...

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Bibliographic Details
Main Authors: Sojeong Jin, Ji-Hyeon Jeon, Sowon Lee, Woo Youl Kang, Sook Jin Seong, Young-Ran Yoon, Min-Koo Choi, Im-Sook Song
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Molecules
Subjects:
ginsenosides
red ginseng extract
pharmacokinetics
human
Online Access:https://www.mdpi.com/1420-3049/24/14/2618

Internet

https://www.mdpi.com/1420-3049/24/14/2618

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