Deposition of mouse amyloid β in human APP/PS1 double and single AD model transgenic mice

The deposition of amyloid β (Aβ) peptides and neurofibrillary tangles are the two characteristic pathological features of Alzheimer's disease (AD). To investigate the relation between amyloid precursor protein (APP) production, amyloid β deposition and the type of Aβ in deposits, i.e., human an...

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Bibliographic Details
Main Authors: Thomas van Groen, Amanda J. Kiliaan, Inga Kadish
Format: Article
Language:English
Published: Elsevier 2006-09-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996106001240