Lysophosphatidic acid increases the electrophysiological instability of adult rabbit ventricular myocardium by augmenting L-type calcium current.

Lysophosphatidic acid (LPA) has diverse actions on the cardiovascular system and is widely reported to modulate multiple ion currents in some cell types. However, little is known about its electrophysiological effects on cardiac myocytes. This study investigated whether LPA has electrophysiological...

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Bibliographic Details
Main Authors: Yong Wei, Li-qun Zhao, Bao-zhen Qi, Xing Xiao, Li He, Gen-qing Zhou, Song-wen Chen, Hong-li Li, Lei Ruan, Cun-tai Zhang, Shao-wen Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3448719?pdf=render