Correlation of TTF-1 immunoexpression and EGFR mutation spectrum in non–small cell lung carcinoma

Correlation of TTF-1 immunoexpression and EGFR mutation spectrum in non–small cell lung carcinoma

Background Thyroid transcription factor (TTF-1) is a diagnostic marker expressed in 75%–85% of primary lung adenocarcinomas (ACs). Activating mutations in the tyrosine kinase domain of the epidermal growth factor receptor (EGFR) gene is the most common targetable driver alteration in lung AC. Previo...

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Bibliographic Details
Main Authors: Tripti Nakra, Varsha Singh, Aruna Nambirajan, Prabhat Singh Malik, Anant Mohan, Deepali Jain
Format: Article
Language:English
Published: Korean Society of Pathologists & the Korean Society for Cytopathology 2021-07-01
Series:Journal of Pathology and Translational Medicine
Subjects:
egfr mutation
lung adenocarcinoma
non–small cell lung carcinoma
thyroid transcription factor-1
uncommon mutations
Online Access:http://www.jpatholtm.org/upload/pdf/jptm-2021-05-10.pdf

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http://www.jpatholtm.org/upload/pdf/jptm-2021-05-10.pdf

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