Immunomodulatory effects of recombinant BCG expressing pertussis toxin on TNF-alpha and IL-10 in a bladder cancer model

Immunomodulatory effects of recombinant BCG expressing pertussis toxin on TNF-alpha and IL-10 in a bladder cancer model

<p>Abstract</p> <p>Background</p> <p>Since successful treatment of superficial bladder cancer with BCG requires proper induction of Th1 immunity, we have developed a rBCG-S1PT strain that induced a stronger cellular immune response than BCG. This preclinical study was d...

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Bibliographic Details
Main Authors: Ramos Kátia L, Srougi Miguel, Andrade Enrico, Leite Luciana CC, Villanova Fabiola E, Nascimento Ivan P, Borra Ricardo C, Chade Daher C, Andrade Priscila M
Format: Article
Language:English
Published: BMC 2008-11-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:http://www.jeccr.com/content/27/1/78

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http://www.jeccr.com/content/27/1/78

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