Blockade of nicotine sensitization by methanol extracts of Glycyrrhizae radix mediated via antagonism of accumbal oxidative stress

Blockade of nicotine sensitization by methanol extracts of Glycyrrhizae radix mediated via antagonism of accumbal oxidative stress

Abstract Background We previously reported that a methanol extract of Glycyrrhizae radix (MEGR) blocked methamphetamine-induced locomotor sensitization and conditioned place preference in rats. In the present study, the effects of MEGR on repeated nicotine-induced locomotor sensitization and enhance...

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Bibliographic Details
Main Authors: Zheng Lin Zhao, Sang Chan Kim, Hong Feng Liu, Yi Yan Wu, Li Bo Li, Yu Hua Wang, Yu Jiao, Yu Fan, Chul Won Lee, Bong Hyeo Lee, Il Je Cho, Chae Ha Yang, Rong Jie Zhao
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Nicotine
Sensitization
Glycyrrhizae radix
Dopamine
Nucleus accumbens
Oxidative stress
Online Access:http://link.springer.com/article/10.1186/s12906-017-1999-2

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http://link.springer.com/article/10.1186/s12906-017-1999-2

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