Taurine rescues mitochondria-related metabolic impairments in the patient-derived induced pluripotent stem cells and epithelial-mesenchymal transition in the retinal pigment epithelium

Mitochondria participate in various metabolic pathways, and their dysregulation results in multiple disorders, including aging-related diseases. However, the metabolic changes and mechanisms of mitochondrial disorders are not fully understood. Here, we found that induced pluripotent stem cells (iPSC...

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Bibliographic Details
Main Authors: Kohei Homma, Ph.D., Eriko Toda, Hideto Osada, Norihiro Nagai, M.D., Ph.D., Takumi Era, M.D., Ph.D., Kazuo Tsubota, M.D., Ph.D., Hideyuki Okano, M.D., Ph.D., Yoko Ozawa, M.D., Ph.D.
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231721000690