3,3′-Diethylthiatricarbocyanine Iodide: A Highly Sensitive Chiroptical Reporter of DNA Helicity and Sequence

3,3′-Diethylthiatricarbocyanine Iodide: A Highly Sensitive Chiroptical Reporter of DNA Helicity and Sequence

Using UV-vis absorption and circular dichroism (CD) spectroscopies, we explored the binding interactions of 3,3′-diethylthiatricarbocyanine iodide (Cy7) with polynucleotides of different sequences and helicity. CD showed to be a very diagnostic tool giving different spectroscopic chiroptical signatu...

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Bibliographic Details
Main Authors: Murtaza Shabbir-Hussain, Mitch Trauernicht, Alessandro D’Urso, Andrea E. Holmes, Milan Balaz, Jung Kyu Choi
Format: Article
Language:English
Published: MDPI AG 2011-11-01
Series:International Journal of Molecular Sciences
Subjects:
Cy7 cyanine dye
left-handed Z-DNA
circular dichroism
DNA recognition
sensing
Online Access:http://www.mdpi.com/1422-0067/12/11/8052/

Internet

http://www.mdpi.com/1422-0067/12/11/8052/

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