PEGylated versus non-PEGylated magnetic nanoparticles as camptothecin delivery system

Camptothecin (CPT; (S)-(+)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione) is a highly cytotoxic natural alkaloid that has not yet found use as chemotherapeutic agent due to its poor water-solubility and chemical instability and, as a consequence, no e...

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Bibliographic Details
Main Authors: Paula M. Castillo, Mario de la Mata, Maria F. Casula, José A. Sánchez-Alcázar, Ana P. Zaderenko
Format: Article
Language:English
Published: Beilstein-Institut 2014-08-01
Series:Beilstein Journal of Nanotechnology
Subjects:
Online Access:https://doi.org/10.3762/bjnano.5.144