Measurement and Modeling of Extra-Column Effects Due to Injection and Connections in Capillary Liquid Chromatography

As column volumes continue to decrease, extra-column band broadening has become an increasingly important consideration when determining column performance. Combined contributions due to the injector and connecting tubing in a capillary LC system were measured and found to be larger than expected by...

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Bibliographic Details
Main Authors: James P. Grinias, Bernard Bunner, Martin Gilar, James W. Jorgenson
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Chromatography
Subjects:
Online Access:http://www.mdpi.com/2227-9075/2/4/669