NLRP3 inflammasome activation in dialyzed chronic kidney disease patients.

NLRP3 inflammasome activation in dialyzed chronic kidney disease patients.

To assess whether NLR pyrin domain-containing protein 3 (NLRP3) inflammasome, a multiprotein complex that mediates the activation of caspase-1 (CASP-1) and pro-inflammatory cytokines IL-18 and IL-1β, could be involved in the chronic inflammatory state observed in chronic kidney disease patients unde...

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Bibliographic Details
Main Authors: Simona Granata, Valentina Masola, Elisa Zoratti, Maria Teresa Scupoli, Anna Baruzzi, Michele Messa, Fabio Sallustio, Loreto Gesualdo, Antonio Lupo, Gianluigi Zaza
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4370586?pdf=render

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http://europepmc.org/articles/PMC4370586?pdf=render

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