Modelling glioblastoma tumour-host cell interactions using adult brain organotypic slice co-culture

Modelling glioblastoma tumour-host cell interactions using adult brain organotypic slice co-culture

Glioblastoma multiforme (GBM) is an aggressive incurable brain cancer. The cells that fuel the growth of tumours resemble neural stem cells found in the developing and adult mammalian forebrain. These are referred to as glioma stem cells (GSCs). Similar to neural stem cells, GSCs exhibit a variety o...

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Bibliographic Details
Main Authors: Maria Angeles Marques-Torrejon, Ester Gangoso, Steven M. Pollard
Format: Article
Language:English
Published: The Company of Biologists 2018-02-01
Series:Disease Models & Mechanisms
Subjects:
Glioblastoma
Adult brain
Niche
Slice culture
Quiescence
Proliferation
Online Access:http://dmm.biologists.org/content/11/2/dmm031435

Internet

http://dmm.biologists.org/content/11/2/dmm031435

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