A general strategy to endow natural fusion-protein-derived peptides with potent antiviral activity.

A general strategy to endow natural fusion-protein-derived peptides with potent antiviral activity.

Fusion between the viral and target cell membranes is an obligatory step for the infectivity of all enveloped virus, and blocking this process is a clinically validated therapeutic strategy.Viral fusion is driven by specialized proteins which, although specific to each virus, act through a common me...

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Bibliographic Details
Main Authors: Antonello Pessi, Annunziata Langella, Elena Capitò, Silvia Ghezzi, Elisa Vicenzi, Guido Poli, Thomas Ketas, Cyrille Mathieu, Riccardo Cortese, Branka Horvat, Anne Moscona, Matteo Porotto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3353973?pdf=render

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http://europepmc.org/articles/PMC3353973?pdf=render

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