Low mechano-afferent fibers reduce thermal pain but not pain intensity in CRPS

Abstract Background Human hairy (not glabrous skin) is equipped with a subgroup of C-fibers, the C-tactile (CT) fibers. Those do not mediate pain but affective aspects of touch. CT-fiber-activation reduces experimental pain if they are intact. In this pilot study we investigated pain modulating capa...

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Bibliographic Details
Main Authors: Kathrin Habig, Gothje Lautenschläger, Hagen Maxeiner, Frank Birklein, Heidrun H. Krämer, Susann Seddigh
Format: Article
Language:English
Published: BMC 2021-07-01
Series:BMC Neurology
Subjects:
QST
Online Access:https://doi.org/10.1186/s12883-021-02304-7