Biological Predictors of Clozapine Response: A Systematic Review

Background: Clozapine is the recommended antipsychotic for treatment-resistant schizophrenia (TRS) but there is significant variability between patients in the degree to which clozapine will improve symptoms. The biological basis of this variability is unknown. Although clozapine has efficacy in TRS...

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Bibliographic Details
Main Authors: Ruta Samanaite, Amy Gillespie, Kyra-Verena Sendt, Grant McQueen, James H. MacCabe, Alice Egerton
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2018.00327/full