Chronopharmacological targeting of Rev-erbα by puerarin alleviates hyperhomocysteinemia in mice

Hyperhomocysteinemia is associated with poor health, including cardiovascular and brain diseases. Puerarin, initially isolated from Puerariae radix, has been shown to possess anti-hyperhomocysteinemia effect. However, the mechanism of puerarin action remains unknown. Here, we uncovered that puerarin...

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Bibliographic Details
Main Authors: Min Chen, Cui Zhou, Haiman Xu, Tianpeng Zhang, Baojian Wu
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220301268