Andrographolide Inhibits Ovariectomy-Induced Bone Loss via the Suppression of RANKL Signaling Pathways

Andrographolide Inhibits Ovariectomy-Induced Bone Loss via the Suppression of RANKL Signaling Pathways

Osteoporosis is a debilitating skeletal disorder with an increased risk of low-energy fracture, which commonly occurs among postmenopausal women. Andrographolide (AP), a natural product isolated from Andrographis paniculata, has been found to have anti-inflammatory, anti-cancer, anti-asthmatic, and...

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Bibliographic Details
Main Authors: Tao Wang, Qian Liu, Lin Zhou, Jin Bo Yuan, Xixi Lin, Rong Zeng, Xiaonan Liang, Jinmin Zhao, Jiake Xu
Format: Article
Language:English
Published: MDPI AG 2015-11-01
Series:International Journal of Molecular Sciences
Subjects:
andrographolide
osteoclastogenesis
RANKL
OVX
bone loss
Online Access:http://www.mdpi.com/1422-0067/16/11/26039

Internet

http://www.mdpi.com/1422-0067/16/11/26039

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