Effects of regional perfusion block in healthy and injured lungs

Effects of regional perfusion block in healthy and injured lungs

Abstract Background Severe hypoperfusion can cause lung damage. We studied the effects of regional perfusion block in normal lungs and in the lungs that had been conditioned by lavage with 500 ml saline and high V T (20 ml kg−1) ventilation. Methods Nineteen pigs (61.2 ± 2.5 kg) were randomized to f...

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Bibliographic Details
Main Authors: Barbara Cambiaghi, Francesco Vasques, Onnen Mörer, Christian Ritter, Tommaso Mauri, Nils Kunze-Szikszay, Karin Holke, Francesca Collino, Giorgia Maiolo, Francesca Rapetti, Elias Schulze-Kalthoff, Tommaso Tonetti, Günter Hahn, Michael Quintel, Luciano Gattinoni
Format: Article
Language:English
Published: SpringerOpen 2017-10-01
Series:Intensive Care Medicine Experimental
Subjects:
Pulmonary embolism
Lung injury
Ventilator-induced lung injury
Experimental animal model
Pulmonary circulation
Computed tomography (CT)
Online Access:http://link.springer.com/article/10.1186/s40635-017-0161-2

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http://link.springer.com/article/10.1186/s40635-017-0161-2

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