Efficacy of the Oral Fluorouracil Pro-drug Capecitabine in Cancer Treatment: a Review

Abstract: Capecitabine (Xeloda®) was developed as a pro-drug of fluorouracil (FU), with the aim of improving tolerability and intratumor drug concentrations through its tumorspecific conversion to the active drug. The purpose of this paper is to review the available information on capecitabine, f...

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Bibliographic Details
Main Authors: John Kouvaris, Haralabos Zabatis, Georgios A. Zacharias, Michael J. Koukourakis, Vassilios Kouloulias, Georgios V. Koukourakis
Format: Article
Language:English
Published: MDPI AG 2008-08-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/13/8/1897/