HIGH-FREQUENCY failure of combination antiretroviral therapy in paediatric HIV infection is associated with unmet maternal needs causing maternal NON-ADHERENCE

HIGH-FREQUENCY failure of combination antiretroviral therapy in paediatric HIV infection is associated with unmet maternal needs causing maternal NON-ADHERENCE

Background: Early combination antiretroviral therapy (cART) reduces the size of the viral reservoir in paediatric and adult HIV infection. Very early-treated children may have higher cure/remission potential. Methods: In an observational study of 151 in utero (IU)-infected infants in KwaZulu-Natal,...

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Bibliographic Details
Main Authors: Jane R. Millar, Nomonde Bengu, Rowena Fillis, Ken Sprenger, Vuyokazi Ntlantsana, Vinicius A. Vieira, Nisreen Khambati, Moherndran Archary, Maximilian Muenchhoff, Andreas Groll, Nicholas Grayson, John Adamson, Katya Govender, Krista Dong, Photini Kiepiela, Bruce D. Walker, David Bonsall, Thomas Connor, Matthew J. Bull, Nelisiwe Nxele, Julia Roider, Nasreen Ismail, Emily Adland, Maria C. Puertas, Javier Martinez-Picado, Philippa C. Matthews, Thumbi Ndung'u, Philip Goulder
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:EClinicalMedicine
Subjects:
Hiv
Hiv cure
Paediatric hiv
Mother-to-child transmission
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537020300882

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http://www.sciencedirect.com/science/article/pii/S2589537020300882

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