Metastatic pancreatic cancer is dependent on oncogenic Kras in mice.

Pancreatic cancer is one of the deadliest human malignancies, and its prognosis has not improved over the past 40 years. Mouse models that spontaneously develop pancreatic adenocarcinoma and mimic the progression of the human disease are emerging as a new tool to investigate the basic biology of thi...

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Bibliographic Details
Main Authors: Meredith A Collins, Jean-Christophe Brisset, Yaqing Zhang, Filip Bednar, Josette Pierre, Kevin A Heist, Craig J Galbán, Stefanie Galbán, Marina Pasca di Magliano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3513322?pdf=render