Risk of Bias in Systematic Reviews of Non-Randomized Studies of Adverse Cardiovascular Effects of Thiazolidinediones and Cyclooxygenase-2 Inhibitors: Application of a New Cochrane Risk of Bias Tool.

Systematic reviews of the effects of healthcare interventions frequently include non-randomized studies. These are subject to confounding and a range of other biases that are seldom considered in detail when synthesizing and interpreting the results. Our aims were to assess the reliability and usabi...

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Bibliographic Details
Main Authors: Anja Bilandzic, Tiffany Fitzpatrick, Laura Rosella, David Henry
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-04-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC4821619?pdf=render