Transcriptional responses of the nerve agent-sensitive brain regions amygdala, hippocampus, piriform cortex, septum, and thalamus following exposure to the organophosphonate anticholinesterase sarin

Transcriptional responses of the nerve agent-sensitive brain regions amygdala, hippocampus, piriform cortex, septum, and thalamus following exposure to the organophosphonate anticholinesterase sarin

<p>Abstract</p> <p>Background</p> <p>Although the acute toxicity of organophosphorus nerve agents is known to result from acetylcholinesterase inhibition, the molecular mechanisms involved in the development of neuropathology following nerve agent-induced seizure are no...

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Bibliographic Details
Main Authors: Meyerhoff James L, Robison Christopher L, Lumley Lucille A, Spradling Kimberly D, Dillman James F
Format: Article
Language:English
Published: BMC 2011-07-01
Series:Journal of Neuroinflammation
Subjects:
Nerve Agent
Chemical Warfare
Organophosphate
Sarin
Seizure
Neuroinflammation
Cytokine
Chemokine
Microarray
Transcriptomics
Online Access:http://www.jneuroinflammation.com/content/8/1/84

Internet

http://www.jneuroinflammation.com/content/8/1/84

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