The cardioprotective effects of carvedilol on ischemia and reperfusion injury by AMPK signaling pathway

The cardioprotective effects of carvedilol on ischemia and reperfusion injury by AMPK signaling pathway

Carvedilol, a third generation beta blocker, is in clinical use for heart failure patients. However, besides adrenergic receptor blockade, the pharmacological effects of carvedilol on cardiomyocytes remain unknown. AMP-activated protein kinase (AMPK) is an emerging target recognized for heart failur...

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Bibliographic Details
Main Authors: Haiyan Hu, Xuan Li, Di Ren, Yi Tan, Jimei Chen, Lei Yang, Ruiping Chen, Ji Li, Ping Zhu
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
AMPK
Carvedilol
Cardioprotection
Ischemia/reperfusion
Online Access:http://www.sciencedirect.com/science/article/pii/S075333221932236X

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http://www.sciencedirect.com/science/article/pii/S075333221932236X

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