QTL Mapping on a Background of Variance Heterogeneity

Standard QTL mapping procedures seek to identify genetic loci affecting the phenotypic mean while assuming that all individuals have the same residual variance. But when the residual variance differs systematically between groups, perhaps due to a genetic or environmental factor, such standard proce...

Full description

Bibliographic Details
Main Authors: Robert W. Corty, William Valdar
Format: Article
Language:English
Published: Oxford University Press 2018-12-01
Series:G3: Genes, Genomes, Genetics
Subjects:
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.118.200790