Huntingtin-associated protein 1 interacts with breakpoint cluster region protein to regulate neuronal differentiation.

Alterations in microtubule-dependent trafficking and certain signaling pathways in neuronal cells represent critical pathogenesis in neurodegenerative diseases. Huntingtin (Htt)-associated protein-1 (Hap1) is a brain-enriched protein and plays a key role in the trafficking of neuronal surviving and...

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Main Authors: Pai-Tsang Huang, Chien-Ho Chen, I-Uen Hsu, Shaima'a Ahmad Salim, Shu-Huei Kao, Chao-Wen Cheng, Chang-Hao Lai, Cheng-Fan Lee, Yung-Feng Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4324908?pdf=render