Novel Hit Compounds as Putative Antifungals: The Case of <i>Aspergillus fumigatus</i>

Novel Hit Compounds as Putative Antifungals: The Case of <i>Aspergillus fumigatus</i>

The prevalence of invasive fungal infections has been dramatically increased as the size of the immunocompromised population worldwide has grown. <i>Aspergillus fumigatus</i> is characterized as one of the most widespread and ubiquitous fungal pathogens. Among antifungal drugs, azoles ha...

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Bibliographic Details
Main Authors: Eftichia Kritsi, Minos-Timotheos Matsoukas, Constantinos Potamitis, Anastasia Detsi, Marija Ivanov, Marina Sokovic, Panagiotis Zoumpoulakis
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Molecules
Subjects:
<i>aspergillus fumigatus</i>
virtual screening
pharmacophore model
molecular docking
antifungal activity
mic
mfc
molecular dynamics simulations
Online Access:https://www.mdpi.com/1420-3049/24/21/3853

Internet

https://www.mdpi.com/1420-3049/24/21/3853

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