miR-34a inhibits migration and invasion of tongue squamous cell carcinoma via targeting MMP9 and MMP14.

BACKGROUND: miR-34a is an important tumor suppressor gene in various cancer types. But little is known about the dysregulation of miR-34a in tongue squamous cell carcinoma (TSCC). In this study, we investigate the expression and potential role of miR-34a in TSCC. METHODS: We evaluated miR-34a expres...

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Bibliographic Details
Main Authors: Ling-Fei Jia, Su-Bi Wei, Keith Mitchelson, Yan Gao, Yun-Fei Zheng, Zhen Meng, Ye-Hua Gan, Guang-Yan Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4182478?pdf=render