Superoxide-mediated ferroptosis in human cancer cells induced by sodium selenite

Superoxide-mediated ferroptosis in human cancer cells induced by sodium selenite

Ferroptosis is a novel form of programmed cell death characterized by an iron-dependent increase in reactive oxygen species (ROS). However, the role of ROS in the regulation of ferroptosis remains elusive. In this study, for the first time, we demonstrate that sodium selenite (SS), a well-establishe...

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Bibliographic Details
Main Authors: Karthikeyan Subburayan, Faisal Thayyullathil, Siraj Pallichankandy, Anees Rahman Cheratta, Sehamuddin Galadari
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Translational Oncology
Subjects:
Deferoxamine
Ferroptosis
Ferrostatin-1
Lipid peroxidation
ROS
Sodium selenite
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523320303351

Internet

http://www.sciencedirect.com/science/article/pii/S1936523320303351

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