Extending the functional characteristics of naturally occurring autoantibodies against β-Amyloid, Prion Protein and α-Synuclein.

BACKGROUND:Abnormal aggregation of proteins induces neuronal cell loss in neurodegenerative disorders such as Alzheimer's Disease, Creutzfeldt-Jakob Disease and Parkinson's Disease. Specific stimuli initialize conformational changes in physiological proteins, causing intra- or extracellula...

Full description

Bibliographic Details
Main Authors: Alexandra Albus, Maike Gold, Jan-Philipp Bach, Monika Burg-Roderfeld, Marit Jördens, Yvonne Kirchhein, Yannick Kronimus, David Mengel, Inga Zerr, Richard Dodel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6114858?pdf=render