Maternal Cytokines CXCL12, VEGFA, and WNT5A Promote Porcine Oocyte Maturation via MAPK Activation and Canonical WNT Inhibition

Maternal Cytokines CXCL12, VEGFA, and WNT5A Promote Porcine Oocyte Maturation via MAPK Activation and Canonical WNT Inhibition

Maternal regulatory factors endow the oocyte with developmental competence in vivo, which might be absent in current in vitro maturation (IVM) systems, thereby compromising oocyte quality. In the present study, by employing RNA sequencing data analysis, we expect to identify potential contributing f...

Full description

Bibliographic Details
Main Authors: Xin Liu, Yuchen Hao, Zhekun Li, Jilong Zhou, Hongmei Zhu, Guowei Bu, Zhiting Liu, Xudong Hou, Xia Zhang, Yi-Liang Miao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
porcine oocyte
CXCL12
VEGFA
WNT5A
in vitro maturation
embryo development
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00578/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.00578/full

Similar Items