Synergistic Activity of the Plant Defensin HsAFP1 and Caspofungin against Candida albicans Biofilms and Planktonic Cultures.

Synergistic Activity of the Plant Defensin HsAFP1 and Caspofungin against Candida albicans Biofilms and Planktonic Cultures.

Plant defensins are small, cysteine-rich peptides with antifungal activity against a broad range of yeast and fungi. In this study we investigated the antibiofilm activity of a plant defensin from coral bells (Heuchera sanguinea), i.e. HsAFP1. To this end, HsAFP1 was heterologously produced using Pi...

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Bibliographic Details
Main Authors: Kim Vriens, Tanne L Cools, Peta J Harvey, David J Craik, Pieter Spincemaille, David Cassiman, Annabel Braem, Jozef Vleugels, Peter H Nibbering, Jan Wouter Drijfhout, Barbara De Coninck, Bruno P A Cammue, Karin Thevissen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4527839?pdf=render

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http://europepmc.org/articles/PMC4527839?pdf=render

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