Self-Nanoemulsifying Drug Delivery System (SNEDDS) for Improved Oral Bioavailability of Chlorpromazine: In Vitro and In Vivo Evaluation

Self-Nanoemulsifying Drug Delivery System (SNEDDS) for Improved Oral Bioavailability of Chlorpromazine: In Vitro and In Vivo Evaluation

<i>Background and Objectives:</i> Lipid-based self-nanoemulsifying drug delivery systems (SNEDDS) have resurged the eminence of nanoemulsions by modest adjustments and offer many valuable opportunities in drug delivery. Chlorpromazine, an antipsychotic agent with poor aqueous solubility&...

Full description

Bibliographic Details
Main Authors: Jeand Baloch, Muhammad Farhan Sohail, Hafiz Shaib Sarwar, Maria Hassan Kiani, Gul Majid Khan, Sarwat Jahan, Muhammad Rafay, Muhammad Tausif Chaudhry, Masoom Yasinzai, Gul Shahnaz
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Medicina
Subjects:
self-nanoemulsifying drug delivery system (SNEDDS)
long-chain triglycerides
chlorpromazine
solubility enhancement
pharmacokinetics
oral bioavailability
Online Access:https://www.mdpi.com/1010-660X/55/5/210

Internet

https://www.mdpi.com/1010-660X/55/5/210

Similar Items