Heterochromatin: an epigenetic point of view in aging

Aging: changes in genome infrastructure Biochemical pathways that alter the physical organization of the genome could play a prominent role in age-related cellular degeneration. Chromosomal DNA is wound around proteins known as histones; when such assemblies are packed closely together, the genes in...

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Bibliographic Details
Main Authors: Jong-Hyuk Lee, Edward W. Kim, Deborah L. Croteau, Vilhelm A. Bohr
Format: Article
Language:English
Published: Nature Publishing Group 2020-09-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-020-00497-4