Orai1 and Stim1 Mediate the Majority of Store-Operated Calcium Entry in Multiple Myeloma and Have Strong Implications for Adverse Prognosis

Orai1 and Stim1 Mediate the Majority of Store-Operated Calcium Entry in Multiple Myeloma and Have Strong Implications for Adverse Prognosis

Background/Aims: Multiple myeloma (MM) is a plasma cell neoplasm which constitutes about 10% of all hematologic malignancies. Despite the development and application of novel agents, MM still undergoes an aggressive and incurable course in the vast majority of patients. Ca2+ is one of the critical r...

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Bibliographic Details
Main Authors: Wei Wang, Yuyue Ren, Lianjie Wang, Weiwei Zhao, Xiushuai Dong, Jiaqi Pan, Haiyan Gao, Yaoyao Tian
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
Soce
Stim1
Orai1
Tumor
Multiple myeloma
Online Access:https://www.karger.com/Article/FullText/492645

Internet

https://www.karger.com/Article/FullText/492645

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