Design, Synthesis, Molecular Docking, Antiapoptotic and Caspase-3 Inhibition of New 1,2,3-Triazole/<i>Bis</i>-2(1<i>H</i>)-Quinolinone Hybrids

A series of novel 1,2,3-triazoles hybridized with two quinolin-2-ones, was designed and synthesized through click reactions. The structures of the synthesized compounds were elucidated by NMR, IR, and mass spectra in addition to elemental analysis. The synthesized compounds were assessed for their a...

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Bibliographic Details
Main Authors: Essmat M. El-Sheref, Ashraf A. Aly, Mohammed B. Alshammari, Alan B. Brown, Sara Mohamed Naguib Abdel-Hafez, Walaa Yehia Abdelzaher, Stefan Bräse, ElShimaa M. N. Abdelhafez
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Molecules
Subjects:
NAC
Online Access:https://www.mdpi.com/1420-3049/25/21/5057