Facile and Convenient One-Pot Process for the Synthesis of Spirooxindole Derivatives in High Optical Purity Using (−)-(S)-Brevicolline as an Organocatalyst

Facile and Convenient One-Pot Process for the Synthesis of Spirooxindole Derivatives in High Optical Purity Using (−)-(S)-Brevicolline as an Organocatalyst

The paper presents an application of the asymmetry approach to spirooxindoles via Brevicolline, Cinchonidine or Cinchonine catalyzed one-pot multicomponent synthesis. Brevicolline, in comparison with Cinchonidine or Cinchonine, catalyzes the reaction of isatins, acetylacetone/ethyl 3-oxobutanoate an...

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Bibliographic Details
Main Authors: Vsevolod Pogrebnoi, Felix Shepeli, Natalia Sucman, Fliur Macaev, Marina Zveaghintseva
Format: Article
Language:English
Published: MDPI AG 2011-04-01
Series:Symmetry
Subjects:
organocatalyzed reactions
spiro[oxindole-3,4'-4'H-pyrane]
Brevicolline
Cinchonidine
Cinchonine
Online Access:http://www.mdpi.com/2073-8994/3/2/165/

Internet

http://www.mdpi.com/2073-8994/3/2/165/

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