A DMSO-free hepatocyte maturation medium accelerates hepatic differentiation of HepaRG cells in vitro

A DMSO-free hepatocyte maturation medium accelerates hepatic differentiation of HepaRG cells in vitro

The most essential tools for studying drug hepatotoxicity, liver diseases, and bioartificial livers have always been models that can recapitulate liver physiology in vitro. The liver progenitor cell line HepaRG represents an effective surrogate of the primary hepatocyte. However, the differentiation...

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Bibliographic Details
Main Authors: Zhen-Yu Wang, Wei-Jian Li, Qi-Gen Li, Hong-Shu Jing, Tian-Jie Yuan, Gong-Bo Fu, Dan Tang, Hong-Dan Zhang, He-Xin Yan, Bo Zhai
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:Biomedicine & Pharmacotherapy
Subjects:
HepaRG
DMSO-free
Hepatocyte maturation medium
Cell differentiation
Hepatotoxicity
3D culture
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219310984

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http://www.sciencedirect.com/science/article/pii/S0753332219310984

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