Clusters of nucleotide substitutions and insertion/deletion mutations are associated with repeat sequences.

The genome-sequencing gold rush has facilitated the use of comparative genomics to uncover patterns of genome evolution, although their causal mechanisms remain elusive. One such trend, ubiquitous to prokarya and eukarya, is the association of insertion/deletion mutations (indels) with increases in...

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Bibliographic Details
Main Authors: Michael J McDonald, Wei-Chi Wang, Hsien-Da Huang, Jun-Yi Leu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-06-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3114760?pdf=render