Corticosteroid-induced immunosuppression ultimately does not compromise the efficacy of antibiotherapy in murine Mycobacterium ulcerans infection.

Corticosteroid-induced immunosuppression ultimately does not compromise the efficacy of antibiotherapy in murine Mycobacterium ulcerans infection.

BACKGROUND: Buruli ulcer (BU) is a necrotizing disease of the skin, subcutaneous tissue and bone caused by Mycobacterium ulcerans. It has been suggested that the immune response developed during the recommended rifampicin/streptomycin (RS) antibiotherapy is protective, contributing to bacterial clea...

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Bibliographic Details
Main Authors: Teresa G Martins, Gabriela Trigo, Alexandra G Fraga, José B Gama, Adhemar Longatto-Filho, Margarida Saraiva, Manuel T Silva, António G Castro, Jorge Pedrosa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3510087?pdf=render

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http://europepmc.org/articles/PMC3510087?pdf=render

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