Inhibition of the Formation In Vitro of Putatively Carcinogenic Metabolites Derived from <i>S. haematobium</i> and <i>O. viverrini</i> by Combination of Drugs with Antioxidants

Inhibition of the Formation In Vitro of Putatively Carcinogenic Metabolites Derived from <i>S. haematobium</i> and <i>O. viverrini</i> by Combination of Drugs with Antioxidants

Infections caused by <i>Schistosoma haematobium</i> and <i>Opisthorchis viverrini</i> are classified as carcinogenic. Although carcinogenesis might be a multifactorial process, it has been postulated that these helminth produce/excrete oxysterols and estrogen-like metabolites...

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Bibliographic Details
Main Authors: Maria João Gouveia, Verónica Nogueira, Bruno Araújo, Fátima Gärtner, Nuno Vale
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Molecules
Subjects:
helminth infections
carcinogenesis
dna adducts
cyp enzymes
antioxidants
drug combination
drug repurposing
Online Access:https://www.mdpi.com/1420-3049/24/21/3842

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https://www.mdpi.com/1420-3049/24/21/3842

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