Ischemic preconditioning in the liver is independent of regulatory T cell activity.

Ischemic preconditioning (IPC) protects organs from ischemia reperfusion injury (IRI) through unknown mechanisms. Effector T cell populations have been implicated in the pathogenesis of IRI, and T regulatory cells (Treg) have become a putative therapeutic target, with suggested involvement in IPC. W...

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Bibliographic Details
Main Authors: Luke R Devey, James A Richards, Richard A O'Connor, Gary Borthwick, Spike Clay, A Forbes Howie, Stephen J Wigmore, Stephen M Anderton, Sarah E M Howie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3504160?pdf=render