Site-Specific Fat-1 Knock-In Enables Significant Decrease of n-6PUFAs/n-3PUFAs Ratio in Pigs

Site-Specific Fat-1 Knock-In Enables Significant Decrease of n-6PUFAs/n-3PUFAs Ratio in Pigs

The fat-1 gene from Caenorhabditis elegans encodes a fatty acid desaturase which was widely studied due to its beneficial function of converting n-6 polyunsaturated fatty acids (n-6PUFAs) to n-3 polyunsaturated fatty acids (n-3PUFAs). To date, many fat-1 transgenic animals have been generated to stu...

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Bibliographic Details
Main Authors: Mengjing Li, Hongsheng Ouyang, Hongming Yuan, Jianing Li, Zicong Xie, Kankan Wang, Tingting Yu, Minghao Liu, Xue Chen, Xiaochun Tang, Huping Jiao, Daxin Pang
Format: Article
Language:English
Published: Oxford University Press 2018-05-01
Series:G3: Genes, Genomes, Genetics
Subjects:
pig
fat-1
genome editing
omega-3 polyunsaturated fatty acids
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.118.200114

Internet

http://g3journal.org/lookup/doi/10.1534/g3.118.200114

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