Assessing the impact on intestinal microbiome and clinical outcomes of antibiotherapy optimisation strategies in haematopoietic stem cell transplant recipients: study protocol for the prospective multicentre OptimBioma study

Introduction Haematopoietic stem cell transplantation (HSCT) is a life-saving treatment for a number of haematological diseases. Graft versus host disease (GVHD) is its main complication and hampers survival. There is strong evidence that intestinal microbiota diversity of the recipient may increase...

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Main Authors: Lucrecia Yáñez, Silvia Jiménez-Jorge, Clara M Rosso-Fernández, Gema Labrador-Herrera, Nancy Rodríguez-Torres, María Eugenia Pachón-Ibáñez, Younes Smani, Francisco José Márquez-Malaver, Carmen Limón Ramos, Carlos Solano, Lourdes Vázquez-López, Mi Kwon, Joan Manuel Mora Barrios, Manuela Aguilar-Guisado, Ildefonso Espigado, Ariadna Pérez Martínez, Peña-Muñoz F, Rebeca Bailen Almorox
Format: Article
Language:English
Published: BMJ Publishing Group 2020-07-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/10/7/e034570.full