Humanin, a Mitochondrial-Derived Peptide Released by Astrocytes, Prevents Synapse Loss in Hippocampal Neurons

Humanin, a Mitochondrial-Derived Peptide Released by Astrocytes, Prevents Synapse Loss in Hippocampal Neurons

Astroglial cells are crucial for central nervous system (CNS) homeostasis. They undergo complex morpho-functional changes during aging and in response to hormonal milieu. Ovarian hormones positively affect different astroglia parameters, including regulation of cell morphology and release of neurotr...

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Bibliographic Details
Main Authors: Sandra Cristina Zárate, Marianela Evelyn Traetta, Martín Gabriel Codagnone, Adriana Seilicovich, Analía Gabriela Reinés
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
astrocytes
ovarian hormones
mitochondria
humanin
synapse
hippocampus
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00123/full

Internet

https://www.frontiersin.org/article/10.3389/fnagi.2019.00123/full

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