Neuroanatomy in mouse models of Rett syndrome is related to the severity of Mecp2 mutation and behavioral phenotypes

Neuroanatomy in mouse models of Rett syndrome is related to the severity of Mecp2 mutation and behavioral phenotypes

Abstract Background Rett syndrome (RTT) is a neurodevelopmental disorder that predominantly affects girls. The majority of RTT cases are caused by de novo mutations in methyl-CpG-binding protein 2 (MECP2), and several mouse models have been created to further understand the disorder. In the current...

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Bibliographic Details
Main Authors: Rylan Allemang-Grand, Jacob Ellegood, Leigh Spencer Noakes, Julie Ruston, Monica Justice, Brian J. Nieman, Jason P. Lerch
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Molecular Autism
Subjects:
Magnetic resonance imaging
Rett syndrome
Mecp2 mouse models
Neuroanatomy
Online Access:http://link.springer.com/article/10.1186/s13229-017-0138-8

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http://link.springer.com/article/10.1186/s13229-017-0138-8

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