Resveratrol supplementation reduces ACE2 expression in human adipose tissue

Angiotensin converting enzyme-2 (ACE2) is the cell-surface receptor enabling cellular entry of SARS-CoV-2. ACE2 is highly expressed in adipose tissue (AT), rendering AT a potential SARS-CoV-2 reservoir contributing to massive viral spread in COVID-19 patients with obesity. Although rodent and cell s...

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Bibliographic Details
Main Authors: Marlies de Ligt, Matthijs K. C. Hesselink, Johanna Jorgensen, Nicole Hoebers, Ellen E. Blaak, Gijs H. Goossens
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Adipocyte
Subjects:
Online Access:http://dx.doi.org/10.1080/21623945.2021.1965315