A Biochemical Approach to Understand the Pathogenesis of Advanced Pulmonary Arterial Hypertension: Metabolomic Profiles of Arginine, Sphingosine-1-Phosphate, and Heme of Human Lung.

A Biochemical Approach to Understand the Pathogenesis of Advanced Pulmonary Arterial Hypertension: Metabolomic Profiles of Arginine, Sphingosine-1-Phosphate, and Heme of Human Lung.

Pulmonary arterial hypertension (PAH) is a vascular disease characterized by persistent precapillary pulmonary hypertension (PH), leading to progressive right heart failure and premature death. The pathological mechanisms underlying this condition remain elusive. Analysis of global metabolomics from...

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Bibliographic Details
Main Authors: Yidan D Zhao, Lei Chu, Kathleen Lin, Elise Granton, Li Yin, Jenny Peng, Michael Hsin, Licun Wu, Amy Yu, Thomas Waddell, Shaf Keshavjee, John Granton, Marc de Perrot
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4552732?pdf=render

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http://europepmc.org/articles/PMC4552732?pdf=render

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