High Molecular Weight Hyaluronan Suppresses Macrophage M1 Polarization and Enhances IL-10 Production in PM<sub>2.5</sub>-Induced Lung Inflammation

High Molecular Weight Hyaluronan Suppresses Macrophage M1 Polarization and Enhances IL-10 Production in PM<sub>2.5</sub>-Induced Lung Inflammation

PM<sub>2.5</sub> is particulate matter with a diameter of 2.5 &#956;m or less. Airway macrophages are the key players regulating PM<sub>2.5</sub>-induced inflammation. High molecular weight hyaluronan (HMW-HA) has previously been shown to exert protective effects on PM<...

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Bibliographic Details
Main Authors: Qiwen Shi, Lan Zhao, Chenming Xu, Leifang Zhang, Hang Zhao
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Molecules
Subjects:
hyalruonan
macrophage polarization
PM<sub>2.5</sub>
inflammation
IL-10
cytokines
Online Access:https://www.mdpi.com/1420-3049/24/9/1766

Internet

https://www.mdpi.com/1420-3049/24/9/1766

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