Continuously Tunable Ca2+ Regulation of RNA-Edited CaV1.3 Channels

Continuously Tunable Ca2+ Regulation of RNA-Edited CaV1.3 Channels

CaV1.3 ion channels are dominant Ca2+ portals into pacemaking neurons, residing at the epicenter of brain rhythmicity and neurodegeneration. Negative Ca2+ feedback regulation of CaV1.3 channels (CDI) is therefore critical for Ca2+ homeostasis. Intriguingly, nearly half the CaV1.3 transcripts in the...

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Bibliographic Details
Main Authors: Hojjat Bazzazi, Manu Ben Johny, Paul J. Adams, Tuck Wah Soong, David T. Yue
Format: Article
Language:English
Published: Elsevier 2013-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713005147

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http://www.sciencedirect.com/science/article/pii/S2211124713005147

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